They will miss him.
Real Madrid were able to see of Bayern Munich in the first leg of their Champions League semi-final las week, scoring two vital away goals in the process. Bayern peppered their goal but they held the hosts to just one goal, while Marcelo and Marco Asensio ensured Madrid emerged victorious.
Their squad is littered with talent, but one of the most important players this season has been Isco. His ability to float around the pitch, find pockets of space and use the ball to great effect has made him almost indispensable in this Madrid side.
Real Madrid will have to do without him in the second leg against Bayern, as he will be ruled out through injury. He picked up a knock during the first leg and was substituted off for Asensio, who may get to take his place in the starting line up.
Spanish newspaper Marca are claiming that a scan has flagged up muscle damage that will keep the playmaker out for three weeks.
Isco was not having his best game, but he would almost certainly have kept his place in the starting XI for the second leg, with Real Madrid hoping to exert control over the game.
Marco Asensio will likely take his place, although this could also pave the way for Gareth Bale to return to the team, after his goal against Leganes today.
